Plot: 1916. Dreaming about saving countless lives and having another adventure, the feisty English feminist and doctor of botany, Dr Lily Houghton, embarks on a peril-laden mission to change the world. Along with her fashionable brother, MacGregor, Dr Houghton enlists the help of the arrogant, wisecracking riverboat skipper, Captain Frank Wolff, to guide them through the serpentine Amazon River in La Quila, his swift wooden boat. Now, as the intrepid trio ventures deeper and deeper into the heart of an impenetrable green maze, searching for something that cannot be found, a centuries-old curse and the ruthless aristocrat, Prince Joachim, threaten to put an end to their ambitious plans. And, sooner or later, the jungle always wins. Is it true that the Spanish conquistador, Don Aguirre, was lost in the same God-forsaken part of the world??
Alternative Plot: Join fan favorites Dwayne Johnson and Emily Blunt for the adventure of a lifetime on Disney's JUNGLE CRUISE, a rollicking thrill-ride down the Amazon with wisecracking skipper Frank Wolff and intrepid researcher Dr. Lily Houghton. Lily travels from London, England to the Amazon jungle and enlists Frank's questionable services to guide her downriver on La Quila--his ramshackle-but-charming boat. Lily is determined to uncover an ancient tree with unparalleled healing abilities--possessing the power to change the future of medicine. Thrust on this epic quest together, the unlikely duo encounters innumerable dangers and supernatural forces, all lurking in the deceptive beauty of the lush rainforest. But as the secrets of the lost tree unfold, the stakes reach even higher for Lily and Frank and their fate--and mankind's--hangs in the balance.