Two years after the events of the first film, Mac (Seth Rogen) and Kelly (Rose Byrne) are trying to sell their home with the arrival of another baby. A couple, Eric (Sam Richardson) and Jessica Baiers (Abbi Jacobson) are looking to buy; the real tor (Liz Cackowski) tells Mac and Kelly that their house is in escrow for 30 days, so the buyers will check in every now and then to make sure everything is okay. Meanwhile, Mac's friend, Jimmy (Ike Barinholtz), and his once-again wife Paula (Carla Gallo) are also expecting a baby. At the Phi Lambda sorority, Shelby (Chloë Grace Moretz), a freshman, learns that sororities are not allowed to host parties, and can only attend frat parties. Shelby goes to a frat party and meets two other freshmen, Beth (Kiersey Clemons) and Nora (Beanie Feldstein)..