Plot: On the initial segment to Memphis, a Chicago to New York bound prisoner transport plane is forced to make an emergency crash landing due to an incident among two of the prisoners on board. In the aftermath of the crash, all aboard are accounted for, except a prisoner named Mark Roberts - one of the two involved in the incident - who is on the run. Roberts, a tow truck driver, was the victim in a serious vehicular accident, the subsequent search finding him to have a concealed firearm and his fingerprints matching those of the person who shot and killed two federal agents. Since being charged, Roberts has plead his innocence, he who believes he is a case of mistaken identity. Chicago-based marshal Sam Gerard, who was on that flight, and his team are placed in charge of tracking down Roberts. Because of the sensitivity of the case, the feds decide to place their own man on Gerard's team, John Royce, who volunteered for this assignment due to his friendship with Roberts' two victims. As the seeming antithesis to each other, Gerard doesn't take too kindly to Royce being placed on his team. In reality, Roberts believes he was framed for the murders in his secret pre-driver life, of which his serious girlfriend, a barista named Marie, knows nothing. He actually knows more about the situation involving the murders than he divulged, his current mission, beyond escaping capture, to find out who framed him and why. Meantime, with more and more evidence in tracking Roberts, Gerard increasingly believes that all with Roberts is not what it appears on the surface, he still determined to do his job to capture Roberts before Roberts exacts his own form of revenge against his framer.
Alternative Plot: An airplane bearing gruff U.S. Marshal Sam Gerard (Tommy Lee Jones) crashes in the wilderness. On board the same flight is Mark Sheridan (Wesley Snipes), a federal prisoner accused of double murder, who escapes during the ensuing chaos, but not before rescuing several people from the wreckage. Gerard is ordered to hunt down the fugitive along with State Department agent John Royce (Robert Downey Jr.), and the two pursue Sheridan relentlessly, despite growing doubts about his guilt.
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