Plot: Clive Nicoli and Elsa Kast are scientists of the Newstead Pharmaceutics researching the splice of DNA from different animals to form new genetic beings and find medical benefits to mankind. They have just created the hybrid Ginger and Fred and now they intend to join together human DNA to alter the genetic structure of their experiment. When the senior management calls off their experiment, they decide to secretly proceed and they generate a life form with human characteristics. They call it Dren and Elsa is very fond of their creation that grows up fast and showing intelligence. When the company shutdown their experiment, they bring Dren to Elsa's abandoned farm and the scientists raise Dren like a daughter. But when it reaches adulthood, the sex drive of Dren is activated and Clive and Elsa learn that they have a serious problem to resolve.
Alternative Plot: Geneticists Clive (Adrien Brody) and Elsa (Sarah Polley) specialize in creating hybrids of species. When they propose the use of human DNA, their pharmaceutical company bosses forbid it, forcing them to conduct experiments in secret. The result is Dren, a creature with amazing intelligence and physical attributes. At first, Dren exceeds their wildest dreams, but as she begins to grow at an accelerated rate, she threatens to become their worst nightmare.
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