Set in Burleson, Texas, between 2008 and 2012, the film centers on a 10-year-old girl named Annabel Beam, daughter of Christy Beam. One day, Anna starts to vomit, and when examined by her doctor, he does not find anything abnormal. On March 20, 2008, Anna wakes up her family at midnight because of an intense stomach pain, severe enough that her parents decide to take her to the hospital. Doctors find no signs of illness, except to say it could be either acid re-flux, or lactose intolerance, but Christy is not convinced by this. The following morning, Christy finally finds a pediatrician in the hospital that is able to diagnose Anna with an abdominal obstruction, and he tells them he must operate immediately or she will die..