Plot: After the death of the Pope, the conclave has gathered in a locked room to choose his successor among four cardinals designated "preferitti". However the quartet is abducted by the Illuminati, a secret brotherhood that was supposed eradicated. The symbologist Robert Langdon and the scientist Vittoria Vetra, who had her powerful and dangerous prototype of antimatter research stolen, are invited by the Vatican police to help them in their investigations. They are received by the receptive Camerlengo, Patrick McKenna, and by the reluctant Commander Richter. They are informed that the Illuminati have promised to kill each cardinal every hour from 8:00 PM and then blow up Vatican City with the antimatter. Robert and Vittoria have a few hours to unravel the clues and discover where the lethal weapon might be hidden.
Alternative Plot: When Harvard symbologist Robert Langdon discovers the resurgence of an ancient brotherhood known as the Illuminati, he flies to Rome to warn the Vatican, the Illuminati's most hated enemy. Joining forces with beautiful Italian scientist Vittoria Vetra (Ayelet Zurer), Langdon follows a centuries-old trail of ancient symbols in the hope of preventing the Illuminati's deadly plot against the Roman Catholic Church from coming to fruition.
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