Plot: Dr. Frank Walton and Dr. Zoe McConnell have been researching a serum named "Lazarus" to help patients in coma to stay alive during interventions for three years in the university sponsored by the Werner-Goss Biotechnical. They bring the documentarian Eva to make a film about their discoveries with their team formed by Niko and Clay and their experiment with a dead dog. However they discover that Lazarus is capable to resurrect the animal that awakes with a different behavior. They decide to keep their discovery in secret, but their project is shut down by the President Dalley claiming that he had an experiment in direct violation of the Review Board. Further, their research is completely stolen by the Crylonis Pharmaceutical that had become shareholder in Werner-Goss. Frank convinces his team to return to the laboratory to duplicate their experiment to prove that they own the patent of the serum, but there is an accident and Zoe is electrocuted and dies. Frank decides to use the Lazarus to resurrect her against the will of his friends but soon the team learns that something is wrong with Zoe, who is Catholic and tells that she is trapped in hell.
Alternative Plot: Medical researcher Frank (Mark Duplass), his fiancee Zoe (Olivia Wilde) and their team have achieved the impossible: they have found a way to revive the dead. After a successful, but unsanctioned, experiment on a lifeless animal, they are ready to make their work public. However, when their dean learns what they've done, he shuts them down. Zoe is killed during an attempt to recreate the experiment, leading Frank to test the process on her. Zoe is revived -- but something evil is within her.
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