David Lyons (played by Gene Wilder), a deaf man, runs a convenience store. He recently hired Wally Karue (Richard Pryor), a blind man. A murder is committed in front of the store and both are present but due to their impairments, can't identify the murderer. Moreover, they are the police's prime suspects and are arrested for the murder. They manage to escape but now they have the police and the actual murderers after them.